This section deals with research pertaining to marijuana and Post-Traumatic Stress Disorder (PTSD). The endocannabinoid system has been shown in research to be significantly intertwined with the same mind and body systems that malfunction in PTSD patients. Research, as with most Cannabis subjects, is only just begun but PTSD seems to be one of the best candidates for medication with Cannabis.
Post-Traumatic Stress Disorder is a mental disorder that may develop after a person is exposed to a traumatic event. Different types of trauma have different odds of developing into full PTSD. Interpersonal trauma such as rape and combat death have the highest rates of PTSD. The symptoms of PTSD persist for more than a month and may often persist for years. Addiction is often seen in PTSD patients as well.
Endocannabinoids interact with many systems involved in PTSD: Extinction of conditioned fear responses in the amygdala due to the CB1 pathway used by THC, anti-depressive effects of THC and CBD, and the sleep-altering and nightmare-suppressing effects of Cannabis. Researchers believe Cannabis can enhance and modify emotional learning and unlearning for victims of PTSD.